Psychiatric-Mental Health Nurse Practitioner Exam

Which medications are recommended for treating African Americans with high blood pressure?

1. ACE inhibitors and ARBs

2. Thiazide diuretics and Calcium Channel Blockers

3. Beta-blockers and ACE inhibitors

4. Alpha-blockers and Thiazide diuretics

The correct answer is: Thiazide diuretics and Calcium Channel Blockers

Thiazide diuretics and Calcium Channel Blockers are particularly recommended for treating hypertension in African Americans due to their effectiveness in this population. Research has shown that these medications tend to lower blood pressure more effectively in Black patients compared to other classes of antihypertensive medications. Thiazide diuretics work by reducing blood volume and inhibiting sodium reabsorption in the kidneys, which helps lower blood pressure. They are often considered first-line therapy for high blood pressure in many patients, but their efficacy is particularly notable in African Americans. Calcium Channel Blockers also play a crucial role as they work by preventing calcium from entering the cells of the heart and blood vessel walls, leading to decreased heart rate and relaxation of blood vessels. This mechanism is beneficial for reducing blood pressure and has been shown to be effective across diverse populations. In contrast, while other classes like ACE inhibitors, ARBs, beta-blockers, and alpha-blockers have their uses, they may not have the same level of efficacy in lowering blood pressure specifically in African American patients as thiazide diuretics and calcium channel blockers. Therefore, the consideration of population-based responses to treatment is critical in effectively managing hypertension in different demographic groups.